SRCSB Day

9:00 Registration
09:45 Welcome

Topic 1 Data Science for Health Research – Chair Nicole Radde

10:00 –10:30 Manfred Claassen, Universitätsklinikum Tübingen: “Learning (from) complex dynamics from single-cell RNA sequencing data”
10:30 –10:40 Franziska Traube, IBC: „Dynamic nuclear localization of glutamate dehydrogenase
during neuronal differentiation“
10:40–10:50 Fabian Klötzer, IZI: “Inferring Functional Protein Distributions from Single-Cell Death Timing”
10:50 – 11:00 Panel discussion
11:00 – 11:30 Coffee & Posters

11:30–11:40 Hyoubi Armel, IBMG: “Enhanced Linear Ubiquitination promotes adipose tissue metabolism and prevents liver injury”
11:40 – 11:50 Lei Wang, IBMG: “G4 quadruplex DNA in gene silencing”
12:00–12:10 Laetitia Wölfle, IMB “Learning to code new genomes”
12:10–12:20 Torsten Riegler und Markus Riegler, SynBio Team, IBMG “Brobiotics: A Synthetic AND-Gate Circuit in E.coli Nissle 1917 for Inflammation-Responsive Drug Delivery in the Gut”

12:20 – 12:35 Panel discussion
12:35–12:45 START-UP Presentation
Ugur Bozuyuk, CellnRoll
“CELLnROLL - A new generation cell sorting platform”

12:45–14:00 Lunch & Posters

Topic 2 Biorobotics and Biomanufacturing–Chair Ralf Takors

14:00–14:30 Selman Sakar,EPFL Lausanne “Robotic micromanipulation of tissues, embryos and insects for life sciences”
14:30–14:40 Barbara Nessiem, IBBS: „Active targeting of Breast Cancer using Janus Particles
for Biochemical Modulation”
14:40–14:50 Theresa Kühn, IBBS “Towards 3D bioprinting of functional skeletal muscle fibers”
14:50–15:00 Samuel Kienzle: “Multivariate Phase-Dependent Optimization of Bioprocesses – Why Timing (of Exposure) Matters”
15:00–15:20 Panel discussion

15:20–16:00 Coffee break & Posters

Topic 3 Signaling in consortia and tissues–Chair Amirreza Aghakhani

16:00–16:30 Karoline Faust, KU Leuven “In silico and in vitro exploration of alternative states in human gut communities”
16:30–16:40 Thao Nguyen, SRCSB: “Coordination of morphogen signaling and cell-cell adhesion regulates intestinal homeostasis and disease
16:40–16:50 Philipp Rathert, IBC: “How cells switch genes off: Network mechanisms of chromatin silencing”
16:50–17:00 Camille Dantzer, IZI: “Decoding DLC1 Tumor Suppressor Loss-Neutrophil Crosstalk in Breast Cancer”

17:00–17:20 Panel discussion

17.30 Wrapup, recreation & food

18:00 Party at the Unithekle, Allmandring 17

Posters

1. Birk Achenbach: „Upcycling literature for predictive modelling“
2. Karen Amaral de Oliveira: „Heterogeneous SMAD2/3 Signaling Drives Cell-to-Cell Variation in TGF-β Target Gene Expression”
3. Georg Bail: “Exploring the Spatial Structure of DNA Methylation”
4. Amir Bani Mohammed Ali: “MORPH - Magnetically-Oriented Remote Precision Heart Catheter”
5. Amatus Beyer: “Model-Based Design for Morphogen-Driven Spatial Patterns in Synthetic Biology”
6. Benjamin Castellaz: “Doubly-Stochastic Inverse Problems – A novel inference framework for population models“
7. Li Congxin: “Time matters: modeling the kinetics of alternative splicing”
8. Camille Dantzer: “Decoding DLC1 TumorSuppressor Loss-Neutrophil Crosstalk in the Metastatic Cascade of Triple Negative Breast Cancer”
9. Jenny Geiger: “Development of a simulation framework to predict responsiveness to apoptosis-inducing drugs”
10. Maria Karg: “Targeted gene integration in CHO cells: Development of a stable landing pad platform”
11. Fabian Klötzer: “Inferring Functional Protein Distributions from Single-Cell Death Timing”
12. Marie-Louise Lemloh: “Core facility AMICA - Multiscale and multidimensional material characterization”
13. Evgenia Magiera: “Media Optimization and PEI-Based Transient Transfection in CHO-K1-Derived Cell Lines”
14. Bahar Pehlivanöz: “Flexural Wave-based Acoustic Manipulation of Hollow core–shell Microparticles for ultrasound-responsive Biomedical Microrobots”
15. Moritz Schweller: “Network-Constrained Stochastic Modeling of Motor Protein Dynamics in Crowded Environments”