Drug transport: transferrin receptor-mediated transcytosis of a TNFR2 agonist across blood-brain barriers (BrainAim) - Development and optimization of proARTOS-TB

Funding period:

01.02.2021 - 31.01.2024

Project description:

Development and optimization of a shuttling-system for the efficient transport of a target-activated receptor agonist across the blood-brain-barrier and the blood-cerebrospinal fluid barrier.

Project partners

1. Responsible project manager and coordinator: Prof. Dr. Gert Fricker, Institute of Pharmacy and Molecular Biotechnology, Heidelberg
2. Prof. Dr. med. Horst Schroten, Mannheim Medical Faculty of the University of Heidelberg, Clinic for Pediatrics and Adolescent Medicine
3. Prof. Dr. Markus Morrison, Institute for Cell Biology and Immunology, University of Stuttgart
4. Dr. Thomas Schirrmann, YUMAB GmbH

Project coordination

Markus Morrison

Prof. Dr.

Director of the SRCSB

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