Completed Projects

List of completed projects at the SRCSB

Search for completed projects

1-4 Targets
Development of novel bispecific antibodies for cancer therapy targeting the receptor tyrosine kinases ErbB4 and EGFR
New insights into Bcl-2 familiy interactions: from biophysics to function
Biomimetic Matrices for the Development of Autologeous Bone and Cartilage Implants
Development of sensitive and robust cell-based biosensor assay platforms using peptide gel matrices
Control of Regulatory Networks with focus on non-coding RNA Subproject: Analysis of Gene Regulatory Networks from a Control Engineering Perspective
Corynebacterium glutamicum
Unraveling the functioning and mechanism of medium additives such as dipeptides for enhancing productivities and titers in cell cultures
DYNAMO: Dynamic Modeling of Signaling Networks
Molecular Dynamics of Membrane Associated Protein Complexes
Exploiting GLIOblastoma intractability to address European research TRAINing needs in translational brain tumour research, cancer systems medicine and integrative multi-omics
HepatoSys "Virtual Liver"
BMBF Funding Initiative "Systems of Life - Systemsbiology"
Develope, improve and optimize immunomodulatory concepts and overcome their current limitations
Information and communication theory in molecular biology
An integrative approach for the analysis of RNA-RNA interactions
Medical Systems Biology "Dr. Jekyll and Mr. Hyde"
A Systems Approach to the Therapy of Nosocomical Infections caused by Candida albicans – A commensal Organism switches to a deadly Pathogen
Melanoma Sensitivity
Aims to elucidate mechanisms of therapy-resistance of melanoma and to identify combinatorial systems biomarkers
Multiscale-Hepatocellular Carcinoma (HCC II)
Systems Biology supports Multiscale Analysis of Imaging, Omics and Clinical Data to improve Diagnosis and Therapy of HCCs
Holistic Multi-Scale Modeling of Targeted Protein Therapeutics Action: Towards Predicting Effective Treatment of Cancer
Predictive Cancer Therapy
Pseudomonas Industrial Biocatalysis
Dynamic modeling and simulation of relevant physiological modules involved in biocatalytic reactions based on metabolite measurements
PSYSMO: Systems Biology of Microorganisms
Systems analysis of process-induced stresses: towards a quantum increase in performance of Pseudomonas putida as the cell factory of choice for white biotechnology
Modeling Regulations of Carbon, Oxygen and Nitrogen in Large-Scale Processes with E.coli
Rhodospirillum rubrum
Biological Re-Engineering and Systems Biological Optimization of the Purple Non-sulphur Bacterium, Rhodospirillum rubrum
Quantum coherence in photosynthetic units of purple bacteria
Integrating the Network of RNA- and Protein-based Regulation
RoBo Yeast
Robustness of Yeast Strains and Bioprocesses for Industrial Production of Novel Compounds
Exploitation of the SECRETory pathway for cancer therapy
First in man study with the selective TNFR1 antagonist ATROSAB and supporting preclinical studies to demonstrate the possible clinical benefit of a selective blockade of the TNFR1
Standardization and orthogonalization of the gene expression flow for robust engineering of NTN (new-to-nature) biological properties
Systems Understanding of Microbial Oxygen-Dependant and Independent Catabolism
Systems Biology as a Driver for Industrial Biotechnology
SysTec Mesenchymal Stem Cells
Systems Biology for Tissue Engineering of Mesenchymal Stem Cells: Integrating Novel Experimental Methods and Mathematical Models
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