- Multiscale-Hepatocellular Carcinoma (HCC II)
Systems Biology Supports Multiscale Analysis of Imaging, Omics and Clinical Data to Improve Diagnosis and Therapy of HCCs. The project is part of the National Funding Initiative and Research Program.
An integrative approach for the analysis of RNA-RNA interactions. This project is part of the National Funding Initiative and Research Program.
Unraveling the functioning and mechanism of medium additives such as dipeptides for enhancing productivities and titers in cell cultures.
- 1-4 Target
Development of novel bispecific antibodies for cancer therapy targeting the receptor tyrosine kinases ErbB4 and EGFR
Using peptide hydrogel technology as a 3D matrix to develop a robust sensitive platform for measurements of molecular kinetics
- Melanoma Sensitivity
Aims to elucidate mechanisms of therapy-resistance of melanoma and to identify combinatorial systems biomarkersy
Holistic Multi-Scale Modeling of Targeted Protein Therapeutics Action: Towards Predicting Effective Treatment of Cancer
Modeling Regulations of Carbon, Oxygen and Nitrogen in Large-Scale Processes with E.coli
Standardization and orthogonalization of the gene expression flow for robust engineering of NTN (new-to-nature) biological properties
Robustness of Yeast Strains and Bioprocesses for Industrial Production of Novel Compounds
- DFG InKoMBio
Information and communication theory in molecular biology
- BMBF "SELECT"
First in man study with the selective TNFR1 antagonist ATROSAB and supporting preclinical studies to demonstrate the possible clinical benefit of a selective blockade of the TNFR1
Biomimetic Matrices for the Development of Autologeous Bone and Cartilage Implants
- HepatoSys "Virtual Liver"
BMBF Funding Initiative "Systems of Life - Systemsbiology"
- DFG "Corynebacterium glutamicum"
The objective is to develop, improve and optimize immunomodulatory concepts and to overcome their current limitations
- BMBF NanoGuide
- Helmholtz CoReNe
Control of Regulatory Networks with focus on non-coding RNA
- Pseudomonas Industrial Biocatalysis
Dynamic modeling and simulation of relevant physiological modules involved in biocatalytic reactions based on metabolite measurements
- EU FP7 "SYSINBIO"
Systems Biology as a Driver for Industrial Biotechnology
- Medical Systems Biology "Dr. Jekyll and Mr. Hyde"
A Systems Approach to the Therapy of Nosocomical Infections caused by Candida albicans - A commensal Organism switches to a deadly Pathogen
- SysMo "PSYSMO"
Systems analysis of process-induced stresses: towards a quantum increase in performance of Pseudomonas putida as the cell factory of choice for white biotechnology
Systems Understanding of Microbial Oxygen-Dependant and Independent Catabolism
- SysTec "Mesenchymal Stem Cells"
Systems Biology for Tissue Engineering of Mesenchymal Stem Cells: Integrating Novel Experimental Methods and Mathematical Models
DYNAMO Molecular Dynamics of Membrane Associated Protein Complexes
Dynamic Modeling of Signaling Networks
- FORSYS Partner "Rhospirillum rubrum"
Re-Engineering and Systems Biological Optimization of the Purple Non-sulphur Bacterium